Retention Time Reproducibility
Retention Time Reproducibility- - pH
pH
Neutrals:
No Influence
Acids:
Acids:
Reduced Retention with Increasing pH
Reduced Retention with Increasing pH
Bases:
Increased Retention with Increasing pH
Up to 10% Change in Retention per 0.1 pH Unit
(Largest shift within +/- 1 pH unit of pKa)
pH
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