Aortic Pressure
Flow from
Ventricular
Ventricle
Pressure
Aortic Valve
The pressure sensor membrane flexes when the pressure on one side is different from the pressure on the other
side, and the electrical properties of the membrane change when it flexes. This allows the sensor to generate an
electrical signal proportional to how much the membrane is flexed, and thus proportional to the difference between
the pressure on the outside of the cannula and the pressure inside. When the Impella
correct position across the aortic valve, the top (outer surface) of the sensor is exposed to the aortic pressure and
the bottom (inner surface) of the sensor is exposed to the ventricular pressure. Therefore, the placement signal is
approximately equal to the difference between the aortic pressure and the ventricular pressure.
120
Systole
80
Diastole
0
Time
P
=
P
-
P
Differential
AO
LV
Pressure difference (P
)
Differential
When the Impella
5.0 Catheter is correctly positioned across the aortic valve, the changes in pressure associated
®
with the cardiac cycle result in a pulsatile placement signal. During diastole, the large pressure difference between
the aorta and the left ventricle creates a large electrical signal. Then at the peak of systole, when the aortic valve
opens, the pressure difference between the aorta and the left ventricle—and thus the electrical signal—is zero.
Thus, the continual pressure changes associated with the cardiac cycle produce the pulsatile (up and down)
waveform seen on the Automated Impella
Impella 5.0 S/N: 123456
2016-07-22 10:09
60
-20
1000
0
Impella Flow
Purge System
5.0
5.2 Max
Purge Flow:
20.0 ml/hr
________________________
4.8 Min
L/min
Purge Pressure: 600 mmHg
Impella
®
5.0 Circulatory Support System
Differential
pressure sensor
Sensor
Flow to
Aorta
Cannula
Aortic pressure
Pressure difference
Left ventricular
pressure
Aortic pressure (P
)
Left ventricular pressure (P
AO
®
Controller display.
AIC SN: IC4186 V5.1
MUTE
ALARM
FLOW
Placement
CONTROL
Signal
(mmHg)
0.0
P-8
0.0
35/2
(17)
DISPLAY
10 sec.
Motor
Current
(mA)
PURGE
800/690
SYSTEM
(745)
10 sec.
System Power
MENU
100%
Membrane
5.0 Catheter is placed in the
®
)
LV
5