H&O Equipments CryoPen Serie Manual Del Usuario página 10

They include:
• Permanent changes in pigmentation. Both hypopigmentation (lightening of the skin)
and hyperpigmentation (darkening of the skin) may occur after cryotherapy.
Both generally last a few months, but can be longer lasting.
Avoid freezing the basal cell layer where melanocytes (pigment producing cells) are located.
• Sensory impairment. Though rare, damage to nerves is possible, particularly in areas where they
lie closer to the surface of the skin, such as the fingers, the wrist, and the area behind the ear.
Reports suggest this will disappear within several months.
• Spattering of the cryogen during spraying, when the end nozzle freezes. The innovation
of CryoPen/CryoProbe is the direct application of nitrous oxide under high pressure (55 bar).
This high pressure jet may cause minor shards of frozen humidity in the air blown away
in a circle of approximately 30cm of diameter.
They will thaw the moment they would eventually touch healthy skin.
• Hair loss. Hair follicles are easily damaged by cryosurgery and permanent hair loss
is not uncommon.
• Pigmented spots. It is common use to not treat pigmented spot in sunny seasons.
Solar lentigines (SL) are flat brown sharply demarcated pigmented lesions that commonly appear
as a sign of aging and photodamage on sun-exposed skin.
• Post-inflammatory hyperpigmentation (PIH) is a frequent concern when treating SL
in darker skin types.
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