,ﻳﻝ
ﺎﻧ
ﻓﻳﻧﺗ
,ﻛﻭﺗﻳﻧﻳﻥ
,, ﻛﻭﻛﺎﻳﻳﻥ
150
,()ﻣﺳﺗﻘﻠﺏ ﺍﻟﻣﻳﺛﺎﺩﻭﻥ
EDDP 300
,ﻳﻥ
, ﺃﻛﺳﻳﺩﻭﺩﻭﻥ, ﻓﻳﻧﺗﺷﻳﻛﻠﻳﺩﻳﻥ, ﺑﺭﻭﺑﻭﻛﺳﻳﻔ
, ﺍﻟﻧﺗﺭﻳﺕ
pH
, (
P.S.
) (, ﺍﻟﻭﺯﻥ ﺍﻟﻧﻭﻋﻲ
ﺍﻟﻁﻭﺭ ﻟﻠﻛﺷﻑ ﺍﻟﺳﺭﻳﻊ ﻟﻠﻭﺟﻭﺩ ﺍﻟﻣﺗﺯﺍﻣﻥ ﻭﺍﻟﻧﻭﻋﻲ ﻟﻠﻣﺧﺩﺭﺍﺕ ﺍﻟﻣﺧﺗﻠﻔﺔ ﻭﺃﻳﺿﺎﺗﻬﺎ ﻓﻲ ﺑﻭﻝ ﺍﻹﻧﺳﺎﻥ. ﻓﻘﻁ ﻟﻼﺳﺗﻌﻣﺎﻝ ﺍﻟﺗﺷﺧﻳﺻﻲ ﺍﻟﻁﺑﻲ ﺃﻭ ﺑﻛﻝ ﺣﺎﻝ
.ﺑﻌﺿﻬﺎ, ﻣﻥ ﺍﻟﻔﺣﻭﺻﺎﺕ ﺍﻟﺑﺳﻳﻁﺔ ﺍﻟﻣﻧﺎﻋﻳﺔ ﺇﻟﻰ ﺍﻹﺟﺭﺍءﺍﺕ ﺍﻟﻣﻌﻘﺩﺓ ﺍﻟﺗﺣﻠﻳﻠﻳﺔ
.ﻟﻠﻔﺣﺹ ﺍﻟﺟﻣﻌﻲ ﻟﻠﺑﻭﻝ ﻟﻬﺩﻑ ﺗﺑﻳﻳﻥ ﺍﻟﻭﺟﻭﺩ ﺍﻟﻣﺗﺯﺍﻣﻥ ﻟﻠﻣﺧﺩﺭﺍﺕ ﺍﻟﻣﺗﻌﺎﻁﺎﺓ ﺍﻟﻣﺧﺗﻠﻔﺔ
ﺩﻭﻥ ﺍﻟﻠﺟﻭء ﺇﻟﻰ
ﺍﻟﻔﺣﺹ ﺍﻟﻣﺗﻌﺩﺩ ﺍﻟﺧﺎﺹ ﺑﺎﻟﻣﺧﺩﺭﺍﺕ ﺍﻷﺣﺎﺩﻱ ﺍﻟﻁﻭﺭ )ﺑﻭﻝ( ﻋﺑﺎﺭﺓ ﻋﻥ ﻓﺣﺹ ﻣﻧﺎﻋﻲ ﻛﺭﻭﻣﺎﺗﻭﻏﺭﺍﻓﻲ ﺑﺗﺩﻓﻖ ﺟﺎﻧﺑﻲ ﻟﻠﺗﺣﺩﻳﺩ ﺍﻟﻧﻭﻋﻲ ﻟﻠﻣﺧﺩﺭﺍﺕ ﺍﻟﺗﺎﻟﻳﺔ
Test
Amphetamine (AMP 300)
Amphetamine (AMP 500)
Amphetamine (AMP)
Barbiturates (BAR)
Benzodiazepines (BZO 200)
Benzodiazepines (BZO)
Buprenorphine (BUP)
Clonazepam (ACL)
Cocaine (COC 150)
Cocaine (COC)
Cotinine (COT)
Fentanyl (FTY)
Heroin (HRN)
Ketamine (KET)
Marijuana (THC 20)
Marijuana (THC)
Marijuana (THC 150)
Methadone (MTD)
Methadone metabolite (EDDP 100)
Methadone metabolite (EDDP 300)
Methamphetamine (MET 300)
Methamphetamine (MET 500)
Methamphetamine (MET)
Methylenedioxymethamphetamine (MDMA)
Morphine (MOP 300)
Opiate (OPI 2000)
Oxycodone (OXY)
Phencyclidine (PCP)
Propoxyphene (PPX)
Tramadol (TRA)
Tricyclic Antidepressants (TCA)
ﺗﻛﻭﻳﻧﺎﺕ ﺍﻟﻔﺣﺹ ﺍﻟﻣﺗﻌﺩﺩ ﺍﻟﺧﺎﺹ ﺑﺎﻟﻣﺧﺩﺭﺍﺕ
ﺃﺳﺑﻘﻳﺔ. ﻟﻠﺣﺻﻭﻝ ﻋﻠﻰ
ﻳﺯﻭ ّ ﺩ ﻧﺗﺎﺋﺞ ﺗﺣﻠﻳﻠﻳﺔ ﻓﻘﻁ
( ﺃﻭ
GC
) ﺍﻻﺳﺗﺷﺭﺍﺏ ﺍﻟﻐﺎﺯﻱ
ﻓﺣﺹ
.ﻲ ﻭﺍﻟﺭﺃﻱ ﺍﻟﻣﻬﻧﻲ, ﻭﺑﺷﻛﻝ ﺧﺎﺹ ﻋﻧﺩﻣﺎ ﺗﻛﻭﻥ ﻧﺗﻳﺟﺔ ﺍﻟﻔﺣﺹ ﺇﻳﺟﺎﺑﻳﺔ
ARABIC
ﺑﻭﺑﺭﻳﻧﻭﺭﻓﻳﻥ, ﻛﻠﻭﻧﺎﺗﺯﻳﺑﺎﻡ, ﻛﻭﻛﺎﻳﻳﻥ
,, ﺑﻳﻧﺗﺯﻭﺩﻳﺎﺗﺯﻳﺑﻳﻥ
,()ﻣﺳﺗﻘﻠﺏ ﺍﻟﻣﻳﺛﺎﺩﻭﻥ
EDDP 100
2000
ﻣﺧﺩﺭﺍﺕ
,
300
ﻣﻳﺛﻳﻠﻳﻥ ﺩﻱ ﺃﻛﺳﻲ ﻣﻳﺛﺎﻧﻔﻳﺗﺎﻣﻳﻥ, ﻣﻭﺭﻓﻳﻥ
PCC
/
OX
) ( ﻟﻠﻣﻭﺍﺩ ﺍﻟﻣﺅﻛﺳﺩﺓ / ﺑﻳﺭﻳﺩﻳﻧﻳﻭﻡ ﻛﻠﻭﺭ ﺍﻟﻛﺭﻭﻣﺎﺕ
d-Amphetamine
d-Amphetamine
d-Amphetamine
Secobarbital
Oxazepam
Oxazepam
Buprenorphine
7-Aminoclonazepam
Benzoylecgonine
Benzoylecgonine
Cotinine
Norfentanyl
6-Acetylmorphine
Ketamine
11-nor-Δ
11-nor-Δ
11-nor-Δ
Methadone
2-Ethylidene-1,5-dimethyl-3,3-dipheylpyrrolidine (EDDP)
2-Ethylidene-1,5-dimethyl-3,3-dipheylpyrrolidine (EDDP)
d-Methamphetamine
d-Methamphetamine
d-Methamphetamine
d,l-Methylenedioxymethamphetamine
Morphine
Morphine
Oxycodone
Phencyclidine
Propoxyphene
Tramadol
Nortriptyline
.(ﺃﺧﺭﻯ ﻣﺭﺗﺑﻁﺔ, ﺑﻣﻭﺟﺏ ﻣﺎ ﻫﻭ ﻣﺷﺎﺭ ﺇﻟﻳﻪ ﻓﻲ ﻻﺋﺣﺔ ﺍﻟﻣ ﻳ ّﺯﺍﺕ ﺍﻟﺗﺣﻠﻳﻠﻳﺔ )ﺍﻟﻣﻭﺟﻭﺩﺓ ﻓﻳﻣﺎ ﻳﻠﻲ
. ﻫﺫﺍ ﺍﻟﻔﺣﺹ
T.V.C.
ﺗﺣﺩﻳﺩﺍ, ﻣﻥ ﺍﻷﻓﺿﻝ ﺍﻟﻠﺟﻭء ﺇﻟﻰ
ﺗﺄﻛﻳﺩ ﻟﻠﻧﺗﺎﺋﺞ ﺍﻟﺗﺣﻠﻳﻠﻳﺔ ﺍﻟﻣﺣﺻﻭﻝ ﻋﻠﻳﻬﺎ ﻫﻧﺎ, ﻣﻥ ﺍﻟﺿﺭﻭﺭﻱ ﺍﻟﻠﺟﻭء ﺇﻟﻰ ﻁﺭﻳﻘﺔ ﻛﻳﻣﻳﺎﺋﻳﺔ ﺑﺩﻳﻠﻳﺔ ﺃﻛﺛﺭ
(. ﻛﻝ ﻧﺗﻳﺟﺔ ﻟﻠﻔﺣﻭﺻﺎﺕ ﺍﻟﺧﺎﺻﺔ ﺑﺎﻟﻣﺧﺩﺭﺍﺕ ﺍﻟﻣﺗﻌﺎﻁﺎﺓ ﺗﺗﻁﻠﺏ ﺍﻟﺗﻘﻳﻳﻡ ﺍﻟﻁﺑ
:ﺇﺭﺷﺎﺩﺍﺕ ﻟﺗﻧﻔﻳﺫ ﺍﻟﻔﺣﺹ ﻟﻬﺩﻑ ﺗﺣﺩﻳﺩ ﺍﻟﻭﺟﻭﺩ, ﻓﻲ ﺍﻟﺑﻭﻝ, ﻟﻭﺍﺣﺩﺓ ﺃﻭ ﺃﻛﺛﺭ ﻣﻥ ﺍﻟﻣﺧﺩﺭﺍﺕ ﺍﻟﺗﺎﻟﻳﺔ
200
, ﺃﻣﻔﻳﺗﺎﻣﻳﻥ, ﺑﺎﺭﺑﻳﺗﻭﺭﺍﺕ, ﺑﻳﻧﺗﺯﻭﺩﻳﺎﺗﺯﻳﺑﻳﻥ
,, ﻣﻳﺛﺎﺩﻭﻥ
150
, ﻣﺎﺭﻳﻭﺍﻧﺎ, ﻣﺎﺭﻳﻭﺍﻧﺎ
T.V.C.
.(
ﻋﻥ
ﻟﻠﻣﺧﺩﺭﺍﺕ ﺍﻟﻣﺧﺗﻠﻔﺔ ﻋﻥ ﻁﺭﻳﻖ ﺍﻟﺑﻭﻝ. ﺍﻟﻔﺣﻭﺻﺎﺕ ﺗﺧﺗﻠﻑ
ﺍﻟﻔﺣﻭﺻﺎﺕ ﺍﻟﻣﻧﺎﻋﻳﺔ ﺗﻌﺗﺑﺭ ﺍﻟﻳﻭﻡ, ﻟﺳﺭﻋﺗﻬﺎ ﻭﺣﺳﺎﺳﻳﺗﻬﺎ, ﺍﻟﻭﺳﻳﻠﺔ ﺍﻷﻓﺿﻝ
Calibrator
-THC-9 COOH
9
-THC-9 COOH
9
-THC-9 COOH
9
ﺍﻟﻭﺣﻳﺩ ﺍﺍﻟﻁﻭﺭ )ﺑﻭﻝ( ﻫﻲ ﻣﻣﻛﻧﺔ ﻣﻊ ﺃﻱ ﺗﻧﺳﻳﻖ ﻣﻥ ﺍﻷﺩﻭﻳﺔ ﺍﻟﺗﺣﻠﻳﻠﻳﺔ ﺍﻟﻣﺫﻛﻭﺭﺓ ﺃﻋﻼﻩ ﺃﻭ ﺩﻭ
ﻥ
()ﺑﻭﻝ
ﻓﺣﺹ ﻣﺗﻌﺩﺩ ﺧﺎﺹ ﺑﺎﻟﻣﺧﺩﺭﺍﺕ ﺃﺣﺎﺩﻱ ﺍﻟﻁﻭﺭ
500
, ﺃﻣﻔﻳﺗﺎﻣﻳﻥ
20
, ﻣﺎﺭﻳﻭﺍﻧﺎ
ﻛﻳﺗﺎﻣﻳﻥ
,
(ﺃﺳﻳﺗﻳﻝ ﻣﻭﺭﻓﻳﻥ
,, ﻣﻳﺛﺎﻣﻔﻳﺗﺎﻣﻳﻥ
500
, ﻣﻳﺛﺎﻣﻔﻳﺗﺎﻣﻳﻥ
300
.ﺗﺭﺍﻣﺎﺩﻭﻝ ﻭﺍﻟﻌﻘﺎﺭﺍﺕ ﺍﻟﻣﺿﺎﺩﺓ ﻟﻼﻛﺗﺋﺎﺏ ﺍﻟﺛﻠﺛﻳﺔ ﺍﻟﺣﻠﻘﺎﺕ
) ﻫﺫﻩ ﺍﻟﻣﺟﻣﻭﻋﺔ ﺗﺷﻣﻝ ﻓﺣﺹ ﺻﻼﺣﻳﺔ ﺍﻟﻌﻳﻧﺔ
CRE
) ( ﻭ ﻛﺭﻳﺎﺗﻳﻧﻳﻥ
GLUT
) (, ﻏﻠﻭﺗﺎﺭﺃﻟﺩﻫﻳﺩ
ﺃﺣﺎﺩﻱ
.ﺍﻟﻣﻬﻧﻲ ﻓﻲ ﺍﻟﺷﺭﺍﺋﺢ ﺍﻟﺯﺟﺎﺟﻳﺔ
ﺍﻻﺳﺗﻌﻣﺎﻝ ﺍﻟﻣﻔﺭﻭﺽ ﻭﻣﻠ ﺧ ّ ﺹ
ﻓﺣﺹ ﺟﻣﻌﻲ ﻟﻠﺗﺣﺩﻳﺩ ﺍﻟﻣﺗﺯﺍﻣﻥ
1
.ﺍﺳﺗﻌﻣﺎﻝ ﺍﻷﺩﻭﺍﺕ ﺃﻭ ﺍﻷﺟﻬﺯﺓ
ﺑﺈﻣﻛﺎﻥ ﻫﺫﺍ ﺍﻟﻔﺣﺹ ﺗﺣﺩﻳﺩ ﻣﻭﺍﺩ
MS
) ﻗﻳﺎﺱ ﺍﻟﻁﻳﻑ ﺍﻟﻛﺗﻠﻲ
58
300
ﺃﻣﻔﻳﺗﺎﻣﻳﻥ
6
) ﺍﻟﻬﻳﺭﻭﻳﻥ
ﻣﻳﺛﺎﻣﻔﻳﺗﺎﻣﻳﻥ
NIT
)
ﻓﺣﺹ ﺗﻔﺎﻋﻠﻲ
Cut-off
(ng/mL)
300
500
1 000
300
200
300
10
100
150
300
100
20
10
1 000
20
50
150
300
100
300
300
500
1 000
500
300
2 000
100
25
300
100
1 000