Stryker PINPOINT PC9000 Manual Del Operador página 35

ICG imaging agent is a sterile, water soluble tricarbocyanine dye with a peak
spectral absorption at 800-810 nm in blood plasma or blood. ICG contains not
more than 5.0% sodium iodide. ICG is to be administered intravenously.
The Sterile Water for Injection, pH of 5.0 to 7.0, provided with the ICG is used to
reconstitute the ICG.
Instructions for preparation, handling and administration of ICG imaging agent are
provided in this chapter.
NOVADAQ does not distribute ICG – ICG imaging agent should be acquired
Note:
through normal hospital channels.
Regulation of ICG varies by country. In certain countries, ICG is not registered for
use as a pharmaceutical product. Contact your local distributor for more
information on the availability of ICG at your location.
WARNING: Refer to the ICG Package Insert prior to use.
Following intravenous injection, ICG is rapidly bound to plasma proteins, primarily
lipoproteins with a lesser and variable binding to albumin (2-30% of total).
Simultaneous arterial and venous blood estimations have shown negligible renal,
peripheral, lung or cerebro-spinal uptake of the ICG. ICG is taken up from the
plasma almost exclusively by the hepatic parenchymal cells and is secreted
entirely into the bile. ICG does not undergo significant enterohepatic recirculation.
ICG has a half-life of 2.5-3.0 minutes.
ICG contains sodium iodide and should be used with caution in patients who have
a history of allergy to iodides or iodinated imaging agents due to a risk of
anaphylaxis.
PINPOINT Endoscopic Fluorescence Imaging System Operator's Manual
29